The course is centered around analyses of a set of aviation data sets and will enable the students to become familiar with data science applications to aviation. Aviation topics to be covered include fundamentals of air traffic control, models of aviation operations, aircraft trajectory prediction and optimization, data sources in aviation, overview of data science methods, role of data science in solving problems in aviation operations such as conflict detection and resolution, traffic flow management, arrivals management and surface operations, airline operations, fuel efficiency, global aviation.